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Press Releases/Publications

Article in several newspapers.

  1. Industry Position on May 2008 Publication by Cherry et al. on Male Infertility and Glycol Ether Exposure in OEM – Downstream User Communication
  2. Recently an article was published in the scientific journal ‘Occupational and Environmental Medicine’ (OEM) claiming an association between male infertility and glycol ethers. The conclusions were based on an epidemiological case-contol study.
     
  3. May 2008: Publication by Cherry et al. on Male Infertility and Glycol Ether Exposure in OEM – Industry Letter to the Editor
  4. This letter to the editor appeared in “OEM Online” on 2 July 2008.
     
  5. Glycol ethers and semen quality: a cross-sectional study among male workers in the Paris Municipality
  6. Occup. Environ. Med. 2007;64;467-473; originally published online 1 Mar 2007; doi:10.1136/oem.2005.023952
     
  7. EPA proposes delisting of ethylene glycol butyl ether (EGBE) as a hazardous air pollutant
  8. The Environmental Protection Agency announced on November 5, 2003 that it would shortly be publishing its proposal to delist ethylene glycol butyl ether from the Clean Air Act Amendments' list of Hazardous Air Pollutants.
     
  9. Cefic - Facts & Figures (September 2011)
  10. The 2011 Cefic European Facts & Figures provides an analysis of the latest competitive trends in the European Chemical industry.
     
  11. 91 substances face scrutiny under REACH
  12. ENDS, 21 October 2011 - The European Chemicals Agency (ECHA) has published the names of the first substances to be evaluated under the REACH regime.
     
  13. Cefic 2011 Facts & Figures
  14. BRUSSELS, December 13, 2011 – Growth in European chemicals output will be weaker than expected this year and next because of heightened business uncertainty and inventory trimming, industry group Cefic said today.
     
  15. French label on indoor air pollution enters force
  16. EndsEurope 6 January 2012 - All new construction and decoration products sold in France from 1 January must bear a label showing the level of volatile organic compounds (VOCs) they emit inside a home.
     
  17. Cefic Chemicals Trends Report Jan. 2012
  18. Jan 30, 2012 - EU Chemicals sector posts 1.5% growth through first 11 months of 2011
     
  19. Chemicals agency launches CLP inventory
  20. EndsEurope, 13 February 2012 -- The European Chemicals Agency (ECHA) has launched an online inventory giving hazard information on more than 100,000 substances. ENDS Europe is Europe's leading environmental news service. A free trial is available by clicking on the following link: http://www.endseurope.com/news?mc=glyc
     
  21. Cefic Chemicals Trends Report, February 2012
  22. 24 February 2012 -- EU chemicals production recorded a 1.1% increase in 2012 compared to 2010, according to the latest Cefic Chemicals Trends Report.
     
  23. Checks show REACH compliance is still patchy
  24. EndsEurope, 27 February 2012 -- Approximately 85% of the REACH registration dossiers checked by the European Chemicals Agency (ECHA) last year needed improvement, according to a report on the agency’s evaluation activities published on Monday. ENDS Europe is Europe's leading environmental news service. A free trial is available by clicking on the following link: http://www.endseurope.com/news?mc=glyc
     
  25. Cefic Chemicals Trends Report June 2012
  26. 5 June 2012 - Second quarter 2012 output growth falls 2% but production improves from 4th quarter 2011.
     
  27. Late pre-registration of substances to be registered in 2013 closing soon
  28. ECHA 25 May 2012 - All substances with phase-in status that are produced or imported into the EU in quantities above 100 tonnes per year must be registered on 31 May 2013 the latest.
     

1. Industry Position on May 2008 Publication by Cherry et al. on Male Infertility and Glycol Ether Exposure in OEM – Downstream User Communication

Recently an article was published in the scientific journal ‘Occupational and Environmental Medicine’ (OEM) claiming an association between male infertility and glycol ethers. The conclusions were based on an epidemiological case-contol study.

Click here to read the full article.

 

 

2. May 2008: Publication by Cherry et al. on Male Infertility and Glycol Ether Exposure in OEM – Industry Letter to the Editor

This letter to the editor appeared in “OEM Online” on 2 July 2008.

Click here to read the full article.

 

 

3. Glycol ethers and semen quality: a cross-sectional study among male workers in the Paris Municipality

L Multigner, E Ben Brik, I Arnaud, J M Haguenoer, P Jouannet, J Auger and F Eustache

Occup. Environ. Med. 2007;64;467-473; originally published online 1 Mar 2007; doi:10.1136/oem.2005.023952

Objectives: Apparent increases in human male reproductive disorders, including low sperm production, may have occurred because of increased chemical exposure. Various glycol ether-based solvents have pronounced adverse effects on sperm production and male fertility in laboratory animals. The authors investigated the effects of past and current exposure to glycol ether-containing products on semen quality and reproductive hormones among men employed by the Paris Municipality.

Methods: Between 2000 and 2001 the authors recruited 109 men who gave semen, blood and urine samples and underwent an andrological examination. Information on lifestyle, occupation, exposure and medical history was obtained by interview. According to their job and chemical products used during the period 1990–2000, men were classified as either occupationally exposed or non-exposed. Current exposure levels to glycol ethers at the time of the study were evaluated by biological monitoring of six urinary metabolites.

Results: Previous exposure to glycol ethers was associated with an increased risk for sperm concentration, for rapid progressive motility and for morphologically normal sperm below the World Health Organization semen reference values. No effect of previous glycol ether exposure on hormones levels was observed. By contrast, current glycol ether exposure levels were low and not correlated with either seminal quality or hormone levels.

Conclusions: This study suggests that most glycol ethers currently used do not impact on human semen characteristics. Those that were more prevalent from the 1960s until recently may have long lasting negative effects on human semen quality.

Click here to read the full article

 

 

4. EPA proposes delisting of ethylene glycol butyl ether (EGBE) as a hazardous air pollutant

EPA Proposes Delisting of Ethylene Glycol Butyl Ether (EGBE) as a Hazardous Air Pollutant

The Environmental Protection Agency (EPA) announced on November 5, 2003 that it would shortly be publishing in the Federal Register its proposal to delist ethylene glycol butyl ether (EGBE) from the Clean Air Act Amendments' (CAAA) list of Hazardous Air Pollutants (HAPs). An EPA decision to delist would mean that EGBE would no longer be subject to the CAAA's Maximum Achievable Control Technology (MACT) requirements, or its residual risk and other requirements. EPA will be receiving comments for 60 days after Federal Register publication and will hold a public hearing if requested.

The American Chemistry Council Ethylene Glycol Ethers Panel (ACC Panel) filed a petition in August 1997 showing why the available evidence indicated that EGBE should be delisted. EPA found the petition complete as of December 21, 1998, and sought comments on the petition on August 3, 1999 (64 Fed. Reg. 42125). All submitted comments supported the petition.

EPA is directed under the CAAA to delist HAPs if there are "adequate data on the health and environmental effects of the substance to determine that emissions, ambient concentrations, bioaccumulation or deposition of the substance may not reasonably be anticipated to cause any adverse effects to human health or adverse environmental effects," Section 112(b)(3)(C). The Federal Register proposal (available at http://www.epa.gov/airlinks/airlinks1.html) indicates the Agency has found the data on EGBE meets this standard.

EPA finds wide margins of safety ("Hazard Quotients") between estimated maximum exposures and lowest toxicity effect levels. Specifically, EPA states maximum human exposures will be 16 to 50 times lower than the lowest level expected to pose any risk to human health. Thus, EPA concludes: "[W]e judge that the potential for human health and environmental effects [from EGBE] is sufficiently low to provide reasonable assurance that such adverse effects will not occur."

EPA also notes that exposure estimates were "at least a factor of 2" higher than what the Agency expects would be the maximum individual exposure and "at least an order of magnitude" less than the Agency's Reference Concentration (RfC) (the level below which the Agency does not expect any adverse health effects).

EPA also reviewed the numerous toxicity studies of EGBE. The proposal includes extensive Agency scientific interpretation of all the toxicity studies (including lifetime animal studies that investigated chronic effects including cancer). The Agency finds these data fully support its RfC for EGBE issued in 1999. EPA includes in the proposal it's most recent interpretation of the NTP study of cancer in mice and rats and concludes that extensive data show that its 1999 RfC is "sufficient" to prevent any cancer risk to humans."

November 2003

This information is brought to you by the member companies of the American Chemistry Council CHEMSTAR Ethylene Glycol Ethers Panel: The Dow Chemical Company, Eastman Chemical Company, Equistar Chemicals, LP, and Shell Chemical Company. For more information, please call your supplier representative, or Dr. Susan A. Lewis, Manager of the EGE Panel at (703) 741-5635 or by E-Mail: Susan_Lewis@americanchemistry.com.

 

 

5. Cefic - Facts & Figures (September 2011)

The European chemical industry in a worldwide perspective

 

 

6. 91 substances face scrutiny under REACH

Read more
ENDS Europe is Europe's leading environmental news service. A free trial is available by clicking on the following link: http://www.endseurope.com/news?mc=glyc

 

 

7. Cefic 2011 Facts & Figures

Read more
ENDS Europe is Europe's leading environmental news service. A free trial is available by clicking on the following link: http://www.endseurope.com/news?mc=glyc

 

 

8. French label on indoor air pollution enters force

Read more

 

 

9. Cefic Chemicals Trends Report Jan. 2012

Chemicals Trends Report Summary

 

 

10. Chemicals agency launches CLP inventory

 

 

11. Cefic Chemicals Trends Report, February 2012

Summary

 

 

12. Checks show REACH compliance is still patchy

More...

 

 

13. Cefic Chemicals Trends Report June 2012

Read more

 

 

14. Late pre-registration of substances to be registered in 2013 closing soon

ECHA press release